Contrast Maps
New generalized method of creating composite maps from group of multiple
subjects
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analysisis performed on the voxel basis
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linear combination (contrast) of various SPMs are calculated, contrats
can be created between various :
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subject groups eg. patient vs. control
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comparisons e.g. different tasks, imaging conditions
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statistics - as for control statistics in the Stroop study
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three final SPM are produced
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cumulative effect : mean statistics value
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statistical significance obtained via randomization
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statistical significance obtained by comparing contrasts calculated for
individual subjects with null hypothesis
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map of correlation between particular contrast and external variable can
be calculated
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age
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behavioral measures
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performance
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clinical parameters
Example of contrast design
Examples of MATLAB programs running contrast maps