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Magnetic Resonance Research Center (MRRC) at Yale University School of Medicine :-The new Yale MRRC is part of a $176 million dollar research and teaching facility at Yale University School of Medicine. The MRRC facility includes 33,000 square feet of laboratory and imaging space. This includes dedicated spaces for MRI/MRS, electrophysiological, and psychological testing, subject preparation and recovery, for computing, and image and data analysis, and a fully equipped electronics shopped with 3 full time electronics engineers. This center houses all of our research magnets and personnel in one contiguous facility. An inventory of the current systems is given below. Note that all of these systems are dedicated 100% to research activity.
Human whole-body
Magnets: ·
A Siemens 3.0T Trio scanner, installed in December of 2002.
This system has a top of the line gradient system with 40mT/m maximum
amplitude, and a slew rate of 200T/m/sec with a 100% duty cycle. It also
includes an 8-channel receiver array head-coil and parallel imaging
capabilities. This system is
dedicated to research studies, primarily focused on the development of
functional MRI, investigation of novel contrast mechanisms, and applications in
Neuroscience, Psychology, and Neurosurgery. · A Siemens 1.5T Sonata scanner that is dedicated to research studies, using conventional anatomic imaging, cardiac imaging, and functional MRI. This system has the same gradient capabilities as the 3T (40mT/m maximum amplitude, and a slew rate of 200T/m/sec with a 100% duty cycle). The system also has an 8-channel receiver array head-coil for parallel imaging applications. The magnet is dedicated to basic radiology/neuroscience research including fMRI and the development of MR imaging approaches for Neurosurgical planning. ·
A Bruker 4.0T human spectrometer that is dedicated to in
vivo spectroscopy. The 4T system
uses a new Bruker Avance console with two SGI Octane computers as hosts. The
magnet is equipped with two actively shielded gradient sets, a 72cm id bore body
set (Magnex Scientific) and a 38cm id head gradient insert (Bruker Instruments).
The head gradient insert has a maximum strength of 45mT/m (X and Y and Z
directions) with a rise time of less than 150 sec for all three axes. It
is equipped with all second order shims and a shielded Z2 and Z0 coil to allow
rapid shim updating. There are four receivers allowing phased array
applications. · Patient monitoring within all of the magnets includes non-invasive measures of heart rate, blood pressure, pulse-oximetry, and end tidal CO2 levels and 40 channel EEG recording. Animal
Magnets · Three Bruker Animal systems (bore size 30cm or less) at 4.7T, 7T, and 11.74T for small animal MR imaging and spectroscopy.
EEG Equipment The Center houses two MR compatible EEG systems: 1. Neuroscan Maglink system with Nu-amps – digital amplifier. Maximum sampling rate with this system is 500Hz. 2. Cognitrace 32-Channel EEG/ERP system (www.ant-software.nl) with a sampling frequency up to 10kHz with 22 bit resolution.
Additional
Support Resources Include · Biochemistry Lab · Electronics and Machine Shops (3 full time staff). Dedicated to the design and building of MR hardware and associate electronics for the development of novel imaging methods and applications. · Patient waiting room, and preparation rooms adjacent to the scanner bays. · A two bed Patient Recovery Room immediately adjacent to the human whole body magnets described above. · Surgical Suites for Animal Studies
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